Wheeler is an experienced philanthropist and works to improve the research technologies and therapeutic strategies in neuroscience, particularly in traumatic brain injury, as well as neuro-rehabilitation and product development in neuro-technology. From the early 1980s until the past decade, Wheeler worked to increase the awareness among her neighbors in the Somerset, Pennsylvania, community of the needs of children. As she raised her son, her voice and her interests were unmistakable in all activities and projects related to children.  Wheeler knew she wanted to dedicate her life to her family and her early years were spent exploring the most important subjects, family, relationships, and community. 

During the last fifteen years, Wheeler has served on many committees, organizational boards, and civic organizational campaigns. She developed strategies, opportunities, and events for community activities that have contributed time, talent, and resources to the institutions for which they were directing their support. Wheeler has been recognized in the Pittsburgh community for her leadership in defining challenges confronting disease advocacy groups and has demonstrated a willingness to assist in building national partnerships to secure resources for these important research areas. 

Currently, Wheeler works with the University and Medical Center in Pittsburgh and is interested in building a national consortium of volunteers to partner with her to help transition science out of the labs and into patients around the world.